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KMID : 0356720000160050339
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Journal of the Korean Society of Coloproctology
2000 Volume.16 No. 5 p.339 ~ p.345
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Four Cases of HNPCC Including Two Cases with Synchronous Stomach Cancer
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Park Seun-Ja
Jung Yeon-Soon
Chang Seong-Hoon
Son Ho-Sung
Lee Byung-Kun
Park Moo-In
Ahn Byung-Kwon
Baek Sung-Uhn
Koo Ja-Young
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Abstract
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Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by early manifestation of colorectal cancer (CRC), occurrence of multiple colorectal tumors and high frequencies of extracolonic malignancies. Evaluation of clinical findings in concert with a well-documented and extended pedigree and genetic studies of colorectal cancer can identify person who are at high risk and who thereby might benefit from targeted early detection and primary prevention programs. Here we report 4 cases of HNPCC including 2 cases with synchronous gastric cancers.
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KEYWORD
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HNPCC, Gastric cancer
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